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In the middle of the 19th century, an era of technological progress began. Achievements in the field of natural science gave a powerful breakthrough in the development of clinical medicine. The possibilities of the diagnostic direction expanded, the first laboratory studies of biomaterials were carried out. And the more discoveries took place in the field of biochemistry, the more accurate and informative the results of the analyzes became. Also during this period, physical methods of diagnosis began to be actively used: listening and percussion, which doctors still use today.

The works of Professor Botkin have brought many innovations in this area of ​​medicine. At the therapeutic clinic, pathophysiological studies were carried out, which had not been done before. The healing properties of various plants were also studied: adonis, lily of the valley and others, after which they began to be used in medical practice.

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The second half of the 19th century was marked by the introduction of new medical industries that studied: diseases and treatment of young patients (pediatrics); pregnancy and childbirth (obstetrics); pathology of the nervous system (neuropathology).

In the late 19th and early 20th centuries, the disciplines of the surgical direction were distinguished. These included: Oncology. Study of tumors of a malignant and benign nature. Urology. This area of ​​medicine deals with diseases of the genital organs of men and the urinary system. Traumatology. Study of traumatic consequences on the human body, their consequences and methods of treatment. Orthopedics. Study of diseases that cause deformation and disorders of the musculoskeletal system. Neurosurgery. Treatment of pathologies of the nervous system by surgical intervention.

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This direction is one of the oldest in the world history of medicine. The knowledge used to treat patients has been accumulating for millennia, but Europeans began to take an interest in it only 60-70 years ago. Many methods of Chinese medicine are considered effective, therefore they are often introduced into their practice by Western doctors.